Well, once we get this release out of the way, I want to look at that config screen. Having a global multiplier for item price is one of the things that could go on there.
The other possibility is that (since I've already been talking about expanding the item format) I could add a price multiplier to the item definition. So, yeah, everything gets auto-priced. But if you want one item to be 5 times more expensive than its effects would allow, you'd be able to do that.
No reason not to do both, I suppose.