If I give the girls a stash of relaxers, they seem to go through them like crazy.
I just tested this: without relaxers, tiredness is raised 4%/day (working double shift movie production at 100% constitution, nice accommodations). And yet they still seem to use two per day if I give them any.
Proposed solution: have girls refrain from using a tiredness-decreasing consumables unless tiredness is a decent fraction of the relieving value. Say, 60%, e.g., so that a quality relaxer (-60) would not be used until tiredness is over 36. Or perhaps 2/3.
Maybe something similar with healing consumables, except with a much lower threshold for use (say, 1/5). You wouldn't use a major item on a scratch, but at the same time, when you're hurt you stop caring about being wasteful.