Hmmmmm.... how old are the girlpacks? I mean, I can't really imagine that being the problem, but I know that at some point girlpacks were updated to a new format, so it is possible I suppose. I don't know how tough it is to update them, but you might consider pulling them all out, testing with a new save and new packs, and if that turns out to be the issue, checking WMEdit to see how irritating it might be to update them. I know Capt has updated a lot of older real girl packs, he might be able to answer questions if you have them.
Another thing it could be might be a really old install with the patch. Are you using your original install with the patched exe, or the one from the front page of this thread? We probably should have said so or re-released it in full, but we decided to just update the exe since nothing else has changed in months (or longer), but you do in fact still need the rest of the guts of the game updated if you're using a much older version. So just to be clear, the correct install of the current game would be to download the full game from the main page of this thread, and then download the patched exe a few posts back. If you drop the patch on an older game, it might ~kinda~ work, but there will likely be problems too.
We'll get the main page updated with the latest full version when we can, Joey's got the lead post so we can't edit it currently, and he's unfortunately absent.