Windows girls:
"listed them as Constructs created by a mad scientist."
If anyone can give me some more background story for this mad scientist, perhaps even a way to open up some of the girls for the player. (How he discovers them) anything related to the scientists personality, or work ethics that'd be great.
Could it be the 'scientist creates the machine, machine evolves and eventually becomes self-conscious, scienstist realizes and turns against his creation, his creation strikes back and kills him' leitmotiv?
No, too many books and films use that

.
Okay, lets say there's a brilliant scientist so focused on his work that have little time to go dating girls -he's too busy to be doing things like flirting. Furthermore, he strongly believes that investing so much time and resources just to be with an impredictable human is ridiculously too risky. Then, one ordinary day, when he's in his lab working on computerized models related to chaos theory mechanics, a fresh idea comes to his mind. Next day he starts some sort of pet project. In the beginning the project is real simple: use chaos theory to simulate human changing perception and personality. He tests the model on a wear, obsolete, damaged droid. The results are beyond his expectations, and the pet project becomes the main project. Through revisions and modifications, models and versions, the droids are closer and closer to real humans. They act like humans, they look like humans... and... wait ¿Why all the droids look like young good looking girls?
The scientist smiles as he caress win98 buttocks "and you've got to see the new 'human reproduction' subroutine"
From now, there are several paths:
1) "Professor as just a scientist path": We all know how IT world operates. Technology soon becomes obsolete, and that's not different with the 'professor' creations. He thought that a good way to put obsolete technology to an use could be sending old models to the outside world to see what happens when they interact with humans. Ahmm... Knowing what they were created for, they will surely honor their main program 'interacting' with an astronomical number of male humans... and females... probably even any other species. Thanks to their 'curiosity' module -installed on purpose- they will tend to stick to 'special' or 'interesting' individuals. Yes, just like you. Random encounter could start with things like "you look interesting (shit, I thought I was watching her, not the oppossite)"
2) "Professor as philantropist path": Well, after enjoying methodically playtesting every single model (sometimes scientific effort is rewarded with the pleasant fruits of knowledge

), he decided that this discovery has to be shared with everyone. So, he gathered some resources, made some time planification, set up a assembly line and entered mass production. The escort droids were a success. In a few years, dear professor creations put and end to women slavery, human whoring and loneliness. It is said some of this droids could be found inside the interdimensional catacombs of Crossgate. Yes, catacombs only girls.
3) "Professor as mad scientist": Let's say professor becomes some sort of Hank Scorpio. While working on new features for the droids, he realized of their potential as weapons and made some modifications and tests. The day of the first field test at last. He was nervous, excited like a child the day before xmas. There was a competitor, there's always one. They worked together when they were younger, they made a discovery, but that moth***cker betrayed professor casting him out and taking all the credit. And the day has come. Professor sent a cute win98 to seduce him, poor bastard. After two months of 'honey' and 'darling', her sweetheart stabbed him to death with a 12-inch kitchen knife. Test complete. It is said 'professor' sells assassin droids to whoever has enough hatred and, of course, money. Random encounter, the girl says something like "Hi, I'm lost (she's lying, I don't like the way she looks at me)" or "Hello, target-san, I'm here to seduce you and kill you". Could be fun, hehehe.